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KMID : 1234520110060020171
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Korean Journal of Urogenital Tract Infection Inflammation
2011 Volume.6 No. 2 p.171 ~ p.177
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Prophylactic Effectiveness of Second Generation Cephalosporin According to Prostatic Operation Methods
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Na Seong-Woong
Hwang Eu-Chang
Jung Seung-Il
Kwon Dong-Deuk
Park Kwang-Sung
Ryu Soo-Bang
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Abstract
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Purpose: There is no definitive standard concerning the use of prophylactic antibiotics for prostatic operations,
except for transurethral resection of prostate (TUR-P). This study prospectively investigated the prophylactic effectiveness of a second generation cephalosporin according to prostatic operation method.
Materials and Methods: From October 2010 to January 2011, prostatic operations were conducted for 67 patients: group I (radical prostatectomy, n=18), group II (TUR-P, n=38), group III (laser TUR-P, n=11) for 11: group III). Prophylactic antibiotics were intravenously administered beginning 1 hour preoperatively and orally with several days postoperatively. Prophylactic effectiveness was evaluated by comparison of urine analysis and presence of bacteriuria.
Results: In group I, no patient had preoperative Foley catheter installation, and mean antibiotic prescription period pre- and post-operatively was 5.83 days and 6.94 days. Five group I patients (27.8%) displayed bacteriuria. In group II, 9 patients had preoperative Foley catheter installation and mean antibiotic prescription period was 3.76 days and 5.68 days, respectively. Five patients (13.2%) had postoperative bacteriuria; two in preoperative catheterized patients and three in preoperative non-catheterized patients. In group III, mean antibiotic prescription period was 1.73 days and 5.09 days, respectively. There was no postoperative bacteriuria.
Conclusions: Prophylactic use of a second generation cephalosporin for prostatic operation, except laser TUR-P, was limited in preventing postoperative pyuria with bacteriuria. There was a tendency of higher occurrence of postoperative bacteriuria in patients with preoperative Foley catheter installation.
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KEYWORD
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Cephalosporin, Surgical procedures, Prostate
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